Your browser doesn't support javascript.
loading
Anticoagulation of pediatric patients with venous thromboembolism in 2023.
van Ommen, C Heleen; Luijnenburg, Saskia E.
Afiliación
  • van Ommen CH; Department of Pediatric Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands. Electronic address: c.vanommen@erasmusmc.nl.
  • Luijnenburg SE; Department of Pediatric Hematology, Sophia Children's Hospital, Erasmus MC, Rotterdam, the Netherlands.
Thromb Res ; 235: 186-193, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38378308
ABSTRACT
Venous thromboembolism (VTE) is a rare and heterozygous disease in children. Management of VTE in children is complicated by age-related differences in epidemiology, recurrent VTE and bleeding risk, hemostatic proteins and pharmacokinetics of anticoagulants. Recently, the choice of anticoagulation has expanded to oral factor IIa and Xa inhibitors, which have been authorized for children for treatment of acute VTE and extended secondary prevention. These drugs have several properties that make them extremely suitable for use in children, including oral administration, antithrombin independence, less interactions with food and drugs and no need for monitoring. Unfortunately, the phase 3 studies had many exclusion criteria, and only a few term neonates and infants were included in these studies. Additional real-world data is needed to make evidence-based recommendations in these age and patient groups, as well.
Asunto(s)
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Hemostáticos / Tromboembolia Venosa Límite: Child / Humans / Infant / Newborn Idioma: En Revista: Thromb Res Año: 2024 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Hemostáticos / Tromboembolia Venosa Límite: Child / Humans / Infant / Newborn Idioma: En Revista: Thromb Res Año: 2024 Tipo del documento: Article
...