Empirically derived dietary patterns are associated with major adverse cardiovascular events, all-cause mortality, and congestive cardiac failure in older men: The Concord Health and Ageing in Men Project.
J Nutr Health Aging
; 28(2): 100020, 2024 02.
Article
en En
| MEDLINE
| ID: mdl-38388114
ABSTRACT
BACKGROUND:
Diet is associated with major adverse cardiovascular events (MACE).OBJECTIVE:
We evaluated the associations between empirically derived dietary patterns and MACE.DESIGN:
Prospective cohort study.SETTING:
The Concord Health and Ageing in Men Project, Sydney, Australia.PARTICIPANTS:
539 community-dwelling older Australian men aged 75 years and older.METHODS:
Men underwent dietary assessment using a validated dietitian-administered diet history questionnaire. Cox regression analyses were conducted between MACE and the three dietary patterns identified from factor analysis. Five-point MACE comprised of all-cause mortality, myocardial infarction (MI), congestive cardiac failure (CCF), coronary revascularisation, and/or ischaemic stroke. Four-point MACE included the four endpoints of MI, CCF, coronary revascularisation, and/or ischaemic stroke, and excluded all-cause mortality.RESULTS:
At a median of 5.3 (IQR 4.6-6.3) years of follow-up, the incidences were five-point MACE 31.2% (n = 168); four-point MACE excluding all-cause mortality 17.8% (n = 96); all-cause mortality 20.1% (n = 111); CCF 11.3% (n = 61); MI 3.7% (n = 20); stroke 3.2% (n = 17); and coronary revascularisation 3.1% (n = 15). In fully adjusted analyses, compared to the bottom tertile, the middle tertile of 'vegetables-legumes-seafood' dietary pattern was associated with reduced five-point MACE (HR 0.67 [95% CI 0.45, 0.99, P = .047]), and CCF (HR 0.31 [95% CI 0.15, 0.65, P = .002]), whilst the middle tertile of 'wholegrains-milk-other fruits' dietary pattern was associated with increased five-point MACE (HR 1.78 [95% CI 1.17, 2.70, P = .007]), four-point MACE (HR 1.92 [95% CI 1.12, 3.30, P = .018]), and CCF (HR 2.33 [95% CI 1.17, 4.65, P = .016]). For the 'discretionary-starchy vegetables-processed meats' dietary pattern, a higher score was associated with increased five-point MACE (HR 1.33 [95% CI 1.09, 1.62, P = .004]), and all-cause mortality (HR 1.63 [95% CI 1.26, 2.12, P < .001]), and compared to the bottom tertile, the top tertile was associated with increased all-cause mortality (HR 2.26 [95% CI 1.27, 4.00, P = .005]).CONCLUSION:
Older men may benefit from consuming a 'vegetables-legumes-seafood' dietary pattern rather than 'discretionary-starchy vegetables-processed meats' and 'wholegrains-milk-other fruits' dietary patterns for the prevention of MACE.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
6_cardiovascular_diseases
/
6_cerebrovascular_disease
/
6_ischemic_heart_disease
/
6_other_circulatory_diseases
Asunto principal:
Isquemia Encefálica
/
Accidente Cerebrovascular
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Accidente Cerebrovascular Isquémico
/
Insuficiencia Cardíaca
/
Infarto del Miocardio
Límite:
Aged
/
Humans
/
Male
País/Región como asunto:
Oceania
Idioma:
En
Revista:
J Nutr Health Aging
Asunto de la revista:
CIENCIAS DA NUTRICAO
/
GERIATRIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Australia