Efficacy of 660 nm Photobiomodulation in Burning Mouth Syndrome Management: A Single-Blind Quasi-Experimental Controlled Clinical Trial.
Photobiomodul Photomed Laser Surg
; 42(3): 225-229, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38407832
ABSTRACT
Background:
Burning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa without any evidence of clinical signs or underlining condition. Several treatment modalities have been utilized with various results and levels of evidence. Lately, photobiomodulation (PBM) has emerged as a noninvasive effective therapy due to its anti-inflammatory and biostimulatory effects, especially the low-power laser setting of red wavelength.Objective:
This single-blind quasi-experimental controlled clinical trial aimed to evaluate the PBM effectiveness at a low level of red laser light in patients with BMS compared with sham control. Materials andmethods:
Thirty patients diagnosed with BMS were consecutively assigned to intervention (PBM therapy) and control (sham) groups. The protocol for PBM dosimetry was as follows laser 660 nm; spot size 0.04 cm2; power output 100 mW; emission mode continuous wave; power density 6 J/cm2; irradiation time 10 sec per point within 1 cm2 surface area of the symptomatic area. The treatment protocol was based on once a week for a total of 10 sessions.Results:
Our results showed no statistically significant difference in reduction of pain intensity between the two groups at all the evaluated timepoints during the course of treatment. However, in both groups, we observed a statistically significant reduction of maximum pain intensity of 50% compared with patient-self reporting before the treatment.Conclusions:
Further randomized clinical trials to validate our positive results with a large sample size with a long-term follow-up and understanding further the sham placebo effect are warranted.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndrome de Boca Ardiente
/
Terapia por Luz de Baja Intensidad
Límite:
Humans
Idioma:
En
Revista:
Photobiomodul Photomed Laser Surg
Año:
2024
Tipo del documento:
Article
País de afiliación:
Brasil