Access to Chiral ß-Boryl δ-Lactones via NHC-Catalyzed [4 + 2] Annulation.
Org Lett
; 26(9): 1965-1969, 2024 Mar 08.
Article
en En
| MEDLINE
| ID: mdl-38418377
ABSTRACT
We report a carbene-catalyzed [4 + 2] annulation of activated esters and ß-borate enones, providing an efficient method to build enantioenriched organoborones with two consecutive stereogenic centers. It is worth noting that this protocol represents a new organocatalytic manner to generate chiral ß-C-B bonds. Moreover, it also greatly enriches the structural diversity of the chiral organoboron compounds.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2024
Tipo del documento:
Article