[Characterization of otorhinolaryngologic manifestations in children with mucopolysaccharide storage disease typeâ
and type â
¡].
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
; 38(3): 221-224;229, 2024 Mar.
Article
en Zh
| MEDLINE
| ID: mdl-38433691
ABSTRACT
Objective:
To analyze the characteristics of otorhinolaryngological clinical manifestations in children with Mucopolysaccharideï¼MPSï¼ type â and type II in order to improve the knowledge of otorhinolaryngologists about this disease.Methods:
Clinical data related to 55 children with MPS type â and type II were retrospectively analyzed to investigate the clinical manifestations of MPS in ENT.Results:
All 40 patientsï¼72.72%ï¼ with MPS had at least one ENT symptom during the course of the disease, with 95% of them having an ENT symptom prior to the diagnosis of MPS; upper airway obstruction was the most common ENT symptomï¼34, 85.00%ï¼, followed by recurrent upper respiratory tract infectionsï¼23, 57.50%ï¼, and lastly, hearing lossï¼11, 27.50%ï¼; all 26 patients had undergone at least one surgical procedure, of which 15ï¼57.69%ï¼ had undergone ENT surgery, and all of these patients underwent ENT surgery before diagnosis. The most common ENT surgery was adenoidectomy.Conclusion:
Early clinical manifestations of MPS patients are atypical, but the early and prevalent appearance of otolaryngologic symptoms and increased awareness of the disease among otolaryngologists has a positive impact on the prognosis of MPS.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedades Nasales
/
Sordera
Límite:
Child
/
Humans
Idioma:
Zh
Revista:
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Año:
2024
Tipo del documento:
Article