N95 respirators alter facial skin physiological functions and lipidome composition in health care personnel.
Skin Res Technol
; 30(3): e13653, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38488420
ABSTRACT
BACKGROUND:
During the coronavirus disease 2019 pandemic, wearing medical respirators and masks was essential to prevent transmission.OBJECTIVE:
To quantify the effects of N95 mask usage by measuring facial skin biophysical characteristics and changes in the lipidome.METHODS:
Sixty healthy volunteers wore N95 respirators for 3 or 6 h. Facial images were acquired and physiological parameters were measured in specific facial areas, before and after mask-wearing. Lipidome analysis was also performed.RESULTS:
After N95 respirator usage, facial erythema was observed in both the 3 and 6 h groups. Both sebum secretion and trans-epidermal water loss increased significantly in mask-covered cheeks and chins after 6 h of mask wearing compared with before mask wearing (p < 0.05). Principal component analysis revealed significant differences in lipid composition after mask wearing compared with before. The ceramide subclass NS exhibited a positive correlation with stratum corneum hydration, whereas the AP subclass was negatively correlated with trans-epidermal water loss in the 6 h group.CONCLUSION:
Prolonged wear of N95 respirators may impair facial skin function and alter lipidome composition.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Dispositivos de Protección Respiratoria
/
Respiradores N95
Límite:
Humans
Idioma:
En
Revista:
Skin Res Technol
Asunto de la revista:
DERMATOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
China