Stereoelectronic effects in RNase-catalysed reactions of dinucleoside phosphate cleavage.
FEBS Lett
; 179(2): 217-20, 1985 Jan 07.
Article
en En
| MEDLINE
| ID: mdl-3855400
ABSTRACT
The rate at which dinucleoside phosphates are cleaved by RNases is supposed to be determined by the mole fraction of enzyme-substrate complexes in which the phosphodiester moiety of a dinucleoside phosphate has a highly reactive conformation. The mole fraction of such complexes for a particular RNase depends on the nature of a nucleoside at the O5'-end of the phosphodiester bond. Experimental data are presented to support this hypothesis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oligonucleótidos
/
Ribonucleasas
Idioma:
En
Revista:
FEBS Lett
Año:
1985
Tipo del documento:
Article