Pathophysiology of Non-Esophageal Eosinophilic Gastrointestinal Disorders.
Immunol Allergy Clin North Am
; 44(2): 299-309, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38575225
ABSTRACT
Eosinophilic gastrointestinal disorder (EGID) is an umbrella term encompassing a group of chronic, immune-mediated disorders characterized by eosinophil-rich inflammation affecting one or more segments of the gastrointestinal tract. A recent consensus in nomenclature and emerging data made possible through multi-center consortia are beginning to unravel the molecular and cellular underpinnings of EGIDs below the esophagus. These emerging findings are revealing both overarching commonalities related to a food allergen-driven, chronic, Th2-mediated immune response as well as location-specific nuances in the pathophysiology of the collective EGIDs. Altogether, these advances offer promise for improved diagnoses and more efficacious interventional strategies.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enteritis
/
Eosinofilia
/
Esofagitis Eosinofílica
/
Gastritis
Límite:
Humans
Idioma:
En
Revista:
Immunol Allergy Clin North Am
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos