Role of Mast Cells in Eosinophilic Gastrointestinal Diseases.
Immunol Allergy Clin North Am
; 44(2): 311-327, 2024 May.
Article
en En
| MEDLINE
| ID: mdl-38575226
ABSTRACT
Mast cells play a central role in the pathogenesis of eosinophilic gastrointestinal disorders (EGIDs), including eosinophilic esophagitis. Their interactions with immune and structural cells, involvement in tissue remodeling, and contribution to symptoms make them attractive targets for therapeutic intervention. More is being discovered regarding the intricate interplay of mast cells and eosinophils. Recent studies demonstrating that depletion of eosinophils is insufficient to improve symptoms of EGIDs have raised the question of whether other cells may play a role in symptomatology and pathogenesis of EGIDs.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enteritis
/
Eosinofilia
/
Esofagitis Eosinofílica
/
Gastritis
Límite:
Humans
Idioma:
En
Revista:
Immunol Allergy Clin North Am
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2024
Tipo del documento:
Article