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Frequency of BRAF V600E immunoexpression in ameloblastomas: a multi-institutional analysis of 86 cases in Latin America and comprehensive review of the literature.
Silveira, F-M; Schuch, L-F; Pereira-Prado, V; Sicco, E; Almeda-Ojeda, O; Molina-Frechero, N; Paparella, M-L; Villarroel-Dorrego, M; Hernadez, M; Bologna-Molina, R.
Afiliación
  • Silveira FM; Department of Diagnostics in Pathology and Oral Medicine Universidad de la República, Montevideo, 16400, Uruguay ronellbologna@odon.edu.uy.
Med Oral Patol Oral Cir Bucal ; 29(4): e509-e516, 2024 Jul 01.
Article en En | MEDLINE | ID: mdl-38615253
ABSTRACT

BACKGROUND:

Paracoccidioidomycosis (PCM) is the leading cause of death among systemic mycoses in Brazil. On the other hand, oral squamous cell carcinoma (OSCC) is the most prevalent malignant neoplasm of the mouth. Both lesions rarely affect the tongue dorsum and may share similar clinical characteristics. This study aimed to retrieve cases of single oral ulcers diagnosed as PCM or OSCC. MATERIAL AND

METHODS:

A cross-sectional retrospective study was conducted. All patients who had a single ulcer on dorsum of the tongue and confirmed diagnosis of PCM or OSCC were evaluated.

RESULTS:

A total of 9 patients (5 women and 4 men) were evaluated, 5 patients had OSCCs (mean age = 69,8 years old), and 4 patients PCM (mean age = 51 years old). Most of the lesions were infiltrated and indurated in the palpation exam. Duration ranged from 1 to 12 months (mean time of 5.2 months and 4.7 months for OSCC and PCM, respectively). OSCC was the main clinical diagnosis hypothesis.

CONCLUSIONS:

Although uncommon, PCM and OSCC should be considered as a differential diagnosis hypothesis in infiltrated ulcers on the tongue dorsum. Incisional biopsy is mandatory to confirm the diagnosis and indicate the appropriate treatment.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ameloblastoma Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Med Oral Patol Oral Cir Bucal Asunto de la revista: ODONTOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Uruguay

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ameloblastoma Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Med Oral Patol Oral Cir Bucal Asunto de la revista: ODONTOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Uruguay
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