Dupilumab treatment of trichothiodystrophy in a child.
Pediatr Dermatol
; 2024 Apr 16.
Article
en En
| MEDLINE
| ID: mdl-38627102
ABSTRACT
Trichothiodystrophy (TTD) is a rare congenital disorder caused by genetic mutations, leading to hair and skin abnormalities. We report successful treatment of a TTD case using dupilumab, a monoclonal antibody targeting IL-4Rα. The patient, a 7-year-old boy, exhibited significant improvement in skin and hair conditions, suggesting the potential of dupilumab as a therapeutic option for TTD. Further research is needed to elucidate its mechanism and efficacy in TTD treatment.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Pediatr Dermatol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Italia