C3 Dominant Collapsing Focal Segmental Glomerulosclerosis - A Report of Two Rare Cases.
Indian J Nephrol
; 34(1): 70-73, 2024.
Article
en En
| MEDLINE
| ID: mdl-38645916
ABSTRACT
Collapsing focal segmental glomerulosclerosis (FSGS) a heterogeneous group of disorders, rather than a single disease entity. Kidney biopsy shows segmental or globally collapsed, sclerotic glomerular capillaries. There is also hypertrophy and hyperplasia of overlying glomerular epithelial cells. Immuno-fluorescence is negative or has non-specific deposits of immunoglobulins and C3. We present two cases of C3 dominant collapsing FSGS. Both the cases were non-responsive to therapy and had a poor outcome. This calls for research to study the role of the complement pathway in the pathogenesis of FSGS.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Indian J Nephrol
Año:
2024
Tipo del documento:
Article
País de afiliación:
India