Treg-tissue cell interactions in repair and regeneration.
J Exp Med
; 221(6)2024 Jun 03.
Article
en En
| MEDLINE
| ID: mdl-38668758
ABSTRACT
Regulatory T (Treg) cells are classically known for their critical immunosuppressive functions that support peripheral tolerance. More recent work has demonstrated that Treg cells produce pro-repair mediators independent of their immunosuppressive function, a process that is critical to repair and regeneration in response to numerous tissue insults. These factors act on resident parenchymal and structural cells to initiate repair in a tissue-specific context. This review examines interactions between Treg cells and tissue-resident non-immune cells-in the context of tissue repair, fibrosis, and cancer-and discusses areas for future exploration.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Regeneración
/
Comunicación Celular
/
Linfocitos T Reguladores
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Exp Med
/
J. exp. med
/
Journal of experimental medicine
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos