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The centrosome: a critical hub for cell cycle regulation.
Yoshino, Yuki; Fang, Zhenzhou; Chiba, Natsuko.
Afiliación
  • Yoshino Y; Department of Cancer Biology, Institute of Aging, Development, and Cancer, Tohoku University, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan; Laboratory of Cancer Biology, Graduate School of Life Sciences, Tohoku University, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan; Department of Cancer Biology, Tohoku University Graduate School of Medicine, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan.
  • Fang Z; Department of Cancer Biology, Institute of Aging, Development, and Cancer, Tohoku University, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan; Laboratory of Cancer Biology, Graduate School of Life Sciences, Tohoku University, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan.
  • Chiba N; Department of Cancer Biology, Institute of Aging, Development, and Cancer, Tohoku University, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan; Laboratory of Cancer Biology, Graduate School of Life Sciences, Tohoku University, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan; Department of Cancer Biology, Tohoku University Graduate School of Medicine, 4-1 Seiryomachi, Aoba-ku, Sendai 980-8575, Japan. Electronic address: natsuko.chiba.c7@tohoku.ac.jp.
Trends Cell Biol ; 34(6): 437-439, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38670849
ABSTRACT
Cyclins and cyclin-dependent kinases (CDKs) localize to the centrosome, but their significance in the cell cycle is unclear. Recently, Roberts et al. revealed that centrosomal cyclin B-CDK is required for mitotic entry and phosphorylation of substrates. This suggests that the centrosome acts as a signaling hub controlling the cell cycle.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ciclo Celular / Quinasas Ciclina-Dependientes / Centrosoma Límite: Animals / Humans Idioma: En Revista: Trends Cell Biol Año: 2024 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ciclo Celular / Quinasas Ciclina-Dependientes / Centrosoma Límite: Animals / Humans Idioma: En Revista: Trends Cell Biol Año: 2024 Tipo del documento: Article País de afiliación: Japón