Experimental Approaches to Scar Modeling through Mechanical Skin Damage and Chemical Burn in Sprague Dawley Rats.
Bull Exp Biol Med
; 176(5): 640-644, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-38733481
ABSTRACT
Creating of a scar model in laboratory animals is the most acceptable option for the preclinical search of scar treatment. However, due to high skin regeneration rate in laboratory rodents, creating an optimal animal model of scar formation is a challenge. Here we describe five methods for modeling a scar tissue in rats that we have tested. These methods allowed achieving different histopathological features and different stages of skin scar formation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Piel
/
Quemaduras Químicas
/
Cicatriz
/
Ratas Sprague-Dawley
/
Modelos Animales de Enfermedad
Límite:
Animals
Idioma:
En
Revista:
Bull Exp Biol Med
Año:
2024
Tipo del documento:
Article
País de afiliación:
Rusia