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Squamous cell carcinoma of the nail in patients with Fitzpatrick phototypes IV-VI: a systematic review.
Chang, Michelle J; Schwartz Kahn, Michelle; Khachemoune, Amor.
Afiliación
  • Chang MJ; Department of Dermatology, State University of New York Downstate Medical Center, Brooklyn, NY, USA.
  • Schwartz Kahn M; Department of Dermatology, Veterans Affairs Medical Center, Brooklyn, New York, USA.
  • Khachemoune A; Department of Dermatology, State University of New York Downstate Medical Center, Brooklyn, NY, USA.
Int J Dermatol ; 2024 May 12.
Article en En | MEDLINE | ID: mdl-38736165
ABSTRACT
Squamous cell carcinoma of the nail unit (nSCC) is a rare malignant tumor of the hand and nail. Although skin cancer rarely affects individuals with phototypes IV-VI, its occurrence in these groups is often associated with greater morbidity and mortality. This study aims to characterize the clinical symptoms, presentations, and treatments of nSCC in patients with darker skin types. A systematic review of PubMed and Embase was performed in May 2023 for all peer-reviewed, English-language nSCC studies involving individuals with Fitzpatrick types IV-VI. Most tumors were located on the fingernails (84%), with the right third finger being the most frequently affected (31%). The nail bed (67%) exhibited a higher prevalence than the lateral/proximal nail folds (33%). The duration of symptoms before diagnosis ranged from 1 month to 7 years. nSCC was most commonly treated with Mohs surgery (38%), followed by amputation (35%). Our study was limited to case reports because of a lack of large nSCC studies that provide information on race or images of each patient. These tumors are generally slow-growing yet often misdiagnosed, leading to delays in presentation and diagnosis. Increased awareness about nSCC in phototype IV-VI individuals will reduce misdiagnoses, unnecessary treatment, and recurrences.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Dermatol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Dermatol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos
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