Prevalence of the cagA Virulence Factor Varies by Race Among Helicobacter pylori -Infected Patients Undergoing Upper Endoscopy.
Clin Transl Gastroenterol
; 15(6): e1, 2024 Jun 01.
Article
en En
| MEDLINE
| ID: mdl-38742743
ABSTRACT
INTRODUCTION:
We designed a race-conscious study to assess the presence of Helicobacter pylori v irulence factor cagA in a retrospective cohort of patients with active H. pylori infection.METHODS:
We compared cagA status by race in gastric tissue samples from 473 patients diagnosed with active H. pylori infection from 2015 to 2019.RESULTS:
H. pylori + Black patients were 2 times more likely to be cagA + than H. pylori + White patients (82% vs 36%, P < .0001).DISCUSSION:
Presence of cagA is common among endoscopy patients with active H. pylori infection; appropriate testing and treatment of H. pylori can both reduce gastric cancer risk and address health disparities.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Bacterianas
/
Helicobacter pylori
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Infecciones por Helicobacter
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Factores de Virulencia
/
Antígenos Bacterianos
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Transl Gastroenterol
Año:
2024
Tipo del documento:
Article
País de afiliación:
Estados Unidos