SARS-CoV-2 shedding, infectivity, and evolution in an immunocompromised adult patient.
Rev Inst Med Trop Sao Paulo
; 66: e28, 2024.
Article
en En
| MEDLINE
| ID: mdl-38747849
ABSTRACT
This study aimed to provide further insight into the evolutionary dynamics of SARS-CoV-2 by analyzing the case of a 40-year-old man who had previously undergone autologous hematopoietic stem cell transplantation due to a diffuse large B-cell lymphoma. He developed a persistent SARS-CoV-2 infection lasting at least 218 days and did not manifest a humoral immune response to the virus during this follow-up period. Whole-genome sequencing and viral cultures confirmed a persistent infection with a replication-positive virus that had undergone genetic variation for at least 196 days after symptom onset.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Huésped Inmunocomprometido
/
Esparcimiento de Virus
/
SARS-CoV-2
/
COVID-19
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Rev Inst Med Trop Sao Paulo
Año:
2024
Tipo del documento:
Article
País de afiliación:
Brasil