Silver-Catalyzed Coupling of Ethynylbenziodoxolones with CO2 and Amines to Afford O-ß-Oxoalkyl Carbamates.
Org Lett
; 26(22): 4600-4605, 2024 Jun 07.
Article
en En
| MEDLINE
| ID: mdl-38780900
ABSTRACT
A novel three-component coupling reaction of ethynylbenziodoxolones (EBXs) with CO2 and amines has been achieved via silver catalysis, thereby providing an efficient method for the construction of a range of structurally diverse and valuable O-ß-oxoalkyl carbamates. The transformation proceeds under mild reaction conditions and exhibits a wide substrate scope and good functional group compatibility. In addition, this strategy could be extended to the synthesis of α-acyloxyketones using carboxylic acids as the nucleophiles to react with EBXs.
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1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
/
Org. lett
/
Organic letters
Asunto de la revista:
BIOQUIMICA
Año:
2024
Tipo del documento:
Article