Pathophysiology of cutaneous T-cell lymphomas: Perspective from a French referral centre.
Immunol Lett
; 268: 106871, 2024 Aug.
Article
en En
| MEDLINE
| ID: mdl-38801999
ABSTRACT
Cutaneous T-cell lymphomas (CTCL) are a diverse group of malignant blood disorders characterized by initial skin infiltration, and sometimes, tumor spreading to lymph nodes, blood, and viscera. Mycosis fungoides is the most common form. Sézary syndrome is a distinctive form of CTCL marked by a significant presence of circulating tumor cells in peripheral blood. These diseases are characterized by the plasticity and heterogeneity of the tumor cells in the different tissue compartments, and a difficulty in identifying these tumor cells for diagnostic purposes and therapeutic monitoring. Progress has been made in the understanding of the pathophysiology of these diseases in recent years, and we provide here a review of these advancements.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Linfoma Cutáneo de Células T
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Immunol Lett
Año:
2024
Tipo del documento:
Article