Timing matters: diurnal variation of maximal fat oxidation and substrate oxidation rates in metabolic syndrome-a randomized crossover study.
Eur J Appl Physiol
; 2024 Jun 04.
Article
en En
| MEDLINE
| ID: mdl-38832982
ABSTRACT
PURPOSE:
The aim of this study was to investigate if diurnal oscillation in maximal fat oxidation (MFO) and substrate oxidation rates during exercise exists in subjects with metabolic syndrome (MetS).METHODS:
In a randomized crossover design, 14 MetS patients were assigned to two graded exercise tests conditions performed in the morning (between 700 and 900 a.m) and in the afternoon (between 400 and 500 p.m). MFO was defined as the highest absolute value of fat oxidation obtained from the average of last 2-min stages during an indirect calorimetry test.RESULTS:
MFO increased by 20.6% from morning to afternoon (p = 0.0002, Cohen's d = 0.52). There was a significant time of day, (p < 0.0001, η2p = 0.76) and intensity effect (p = 0.002, η2p = 0.32) in fat oxidation (Fatox) rates indicating that Fatox was higher in the afternoon than in the morning.CONCLUSION:
Our study extends previous findings on the existence of diurnal variation in maximal fat oxidation to MetS patients, highlighting the afternoon as a more favorable time for fat utilization during exercise. These findings have practical implications for optimizing training timing in MetS patients. TRIAL REGISTRATION NUMBER PACTR202306776991260.
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Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
Eur J Appl Physiol
Asunto de la revista:
FISIOLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Túnez