Red-shifted two-photon-sensitive phenanthridine photocages: synthesis and characterisation.

Attiach, Célest M; Kumar, Amit; Daniel, Jonathan; Blanchard-Desce, Mireille; Maruani, Antoine; Dalko, Peter I

Attiach, Célest M; Kumar, Amit; Daniel, Jonathan; Blanchard-Desce, Mireille; Maruani, Antoine; Dalko, Peter I.

Afiliación

Attiach CM; Université Paris Cité, CNRS, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, 75006 Paris, France. antoine.maruani@cnrs.fr.
Kumar A; Université Paris Cité, CNRS, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, 75006 Paris, France. antoine.maruani@cnrs.fr.
Daniel J; Univ. Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255, F-33400 Talence, France.
Blanchard-Desce M; Univ. Bordeaux, CNRS, Bordeaux INP, ISM, UMR 5255, F-33400 Talence, France.
Maruani A; Université Paris Cité, CNRS, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, 75006 Paris, France. antoine.maruani@cnrs.fr.
Dalko PI; Université Paris Cité, CNRS, Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques, 75006 Paris, France. antoine.maruani@cnrs.fr.

Chem Commun (Camb) ; 2024 Jul 16.

Article en En | MEDLINE | ID: mdl-39011868

ABSTRACT

ABSTRACT

Herein we describe the rational design, synthesis and photophysical study of a novel class of phenanthridine-based, one- and two-photon sensitive, photoremovable protecting groups with absorption wavelengths extending beyond 400 nm. This design facilitated the development of scaffolds with enhanced uncaging quantum yield, paving the way for broader applications in controlled drug delivery and molecular manipulation.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Francia

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