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Association between early central venous pressure measurement and all-cause mortality in critically ill patients with heart failure: A cohort of 11,241 patients.
Liang, Benhui; Tang, Yiyang; Chen, Qin; Zhong, Jiahong; Peng, Baohua; Sun, Jing; Wu, Tingting; Zeng, Xiaofang; Feng, Yilu; Yu, Zaixin; Zha, Lihuang.
Afiliación
  • Liang B; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Tang Y; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Chen Q; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Zhong J; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Peng B; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Sun J; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Wu T; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Zeng X; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Feng Y; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Yu Z; Department of Cardiology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Zha L; National Clinical Research Center for Geriatric Disorders (Xiang Ya), Changsha, Hunan, China.
Heliyon ; 10(13): e33599, 2024 Jul 15.
Article en En | MEDLINE | ID: mdl-39040401
ABSTRACT

Background:

The timing of central venous pressure (CVP) measurement may play a crucial role in heart failure management, yet no studies have explored this aspect.

Methods:

Clinical information pertaining to patients in critical condition with a diagnosis of heart failure was retrieved from the MIMIC-IV database. The association between initial measurements of central venous pressure (CVP) and the incidence of mortality from all causes was analyzed using the Cox proportional hazards approach. Subgroup analysis and propensity score matching were conducted for sensitivity analyses.

Results:

This study included 11,241 participants (median age, 75 years; 44.70 % female). Utilizing restricted cubic spline and Kaplan-Meier survival analyses, it was determined that prognostic outcomes were better when CVP was measured within the initial 5-h window. Multivariate-adjusted 1-year (HR 0.69; 95 % CI 0.61-0.77), 90-day (HR 0.70; 95 % CI 0.62-0.80), and 30-day (HR 0.67; 95 % CI 0.57-0.78) all-cause mortalities were significantly lower in patients with early CVP measurement, which was proved robustly in subgroup analysis. Subsequent to the application of propensity score matching, a cohort of 1536 matched pairs was established, with the observed mortality rates continuing to be significantly lower among participants who underwent early CVP assessment.

Conclusions:

Early CVP measurement (within 5 h) demonstrated an independent correlation with a decrease in both immediate and extended all-cause mortality rates among patients in critical condition suffering from heart failure.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: China
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