Your browser doesn't support javascript.
loading
Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation.
Hernández, Damián; Morgan Schlicht, Stephanie; Elli Clarke, Jordan; Daniszewski, Maciej; Karch, Celeste M; Goate, Alison M; Pébay, Alice.
Afiliación
  • Hernández D; Department of Anatomy and Physiology, the University of Melbourne, Parkville, VIC 3010, Australia.
  • Morgan Schlicht S; Department of Anatomy and Physiology, the University of Melbourne, Parkville, VIC 3010, Australia.
  • Elli Clarke J; Department of Anatomy and Physiology, the University of Melbourne, Parkville, VIC 3010, Australia.
  • Daniszewski M; Department of Anatomy and Physiology, the University of Melbourne, Parkville, VIC 3010, Australia.
  • Karch CM; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.
  • Goate AM; Department of Genetics and Genomic Sciences, Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA.
  • Pébay A; Department of Anatomy and Physiology, the University of Melbourne, Parkville, VIC 3010, Australia; Department of Surgery, Royal Melbourne Hospital, the University of Melbourne, Parkville, VIC 3010, Australia. Electronic address: apebay@unimelb.edu.au.
Stem Cell Res ; 79: 103495, 2024 Sep.
Article en En | MEDLINE | ID: mdl-39079290
ABSTRACT
We report the generation of a gene-edited human induced pluripotent stem cell (iPSC) line from an Alzheimer's disease patient-derived iPSC line harbouring the PSEN1 H163R mutation. This line demonstrates pluripotent stem cell morphology, expression of pluripotency markers, and maintains a normal karyotype.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presenilina-1 / Células Madre Pluripotentes Inducidas / Enfermedad de Alzheimer Límite: Humans Idioma: En Revista: Stem Cell Res Año: 2024 Tipo del documento: Article País de afiliación: Australia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presenilina-1 / Células Madre Pluripotentes Inducidas / Enfermedad de Alzheimer Límite: Humans Idioma: En Revista: Stem Cell Res Año: 2024 Tipo del documento: Article País de afiliación: Australia