The Effects of Gluten on Weight Gain, Hematological, Biochemical, and Various Endocrinological Parameters.
Turk J Gastroenterol
; 35(3): 178-185, 2024 Mar.
Article
en En
| MEDLINE
| ID: mdl-39128121
ABSTRACT
BACKGROUND/AIMS:
This study is aimed to compare the effects of nutrition which has been enriched with different amounts of gluten to gluten-free diets on weight gain, diabetogenic state, hematological, and biochemical parameters. MATERIALS ANDMETHODS:
A total of 40 newly weaned male Wistar albino rats used in the study were randomized into 4 different groups based on the gluten rations they were given. Following 12 weeks of diet they were killed and intracardiac blood samples were collected. Groups were identified as group 1 (n = 10) control group; normal rat ration containing wheat, group 2 (n = 10) gluten-free diet, group 3 (n = 10) ration containing medium level of gluten (normal rat diet+6% vital gluten) and group 4 (n = 10) ration containing high level of gluten (normal rat diet+12% vital gluten).RESULTS:
In groups 3 and 4, high-density lipoprotein was found to be higher than the other 2groups. However, when group 2 results were compared to the other groups; the highest T3, T4, creatinine and B12 levels and the lowest gluten-specific IgE level were observed. alanine aminotransferase and aspartate aminotransferase levels were found to be higher in group 1 compared to the other 3 groups. No statistically significant difference was detected between the groups in terms of other parameters.CONCLUSION:
This study provides evidence that a gluten-containing diet does not cause weight gain, has no diabetogenic effect, and also does not adversely affect general health in relation to hematological, biochemical, and various endocrinological parameters.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aumento de Peso
/
Ratas Wistar
/
Dieta Sin Gluten
/
Glútenes
Límite:
Animals
Idioma:
En
Revista:
Turk J Gastroenterol
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2024
Tipo del documento:
Article
País de afiliación:
Turquía