MASS cohort: Multicenter, longitudinal, and prospective study of the role of microbiome in severe pneumonia and host susceptibility.

Wei, Xin; Guo, Li; Cai, Hongliu; Gu, Silan; Tang, Lingling; Leng, Yuxin; Cheng, Minghui; He, Guojun; Han, Yijiao; Ren, Xindie; Lin, Baoyue; Lv, Longxian; Shao, Huanzhang; Wang, Mingqiang; Wang, Hongyu; Dang, Dan; Wang, Shengfeng; Wang, Nan; Shen, Peng; Wang, Qianqian; Xu, Yinghe; Jiang, Yongpo; Zhang, Ning; He, Xuwei; Deng, Xuntao; Dai, Muhua; Zhong, Lin; Xiong, Yonghui; Pan, Yujie; Tang, Kankai; Liu, Fengqi; Yang, Bin; Ren, Lili; Wang, Jianwei; Jiang, Chao; Huang, Lingtong

Wei, Xin; Guo, Li; Cai, Hongliu; Gu, Silan; Tang, Lingling; Leng, Yuxin; Cheng, Minghui; He, Guojun; Han, Yijiao; Ren, Xindie; Lin, Baoyue; Lv, Longxian; Shao, Huanzhang; Wang, Mingqiang; Wang, Hongyu; Dang, Dan; Wang, Shengfeng; Wang, Nan; Shen, Peng; Wang, Qianqian; Xu, Yinghe; Jiang, Yongpo; Zhang, Ning; He, Xuwei; Deng, Xuntao; Dai, Muhua; Zhong, Lin; Xiong, Yonghui; Pan, Yujie; Tang, Kankai; Liu, Fengqi; Yang, Bin; Ren, Lili; Wang, Jianwei; Jiang, Chao; Huang, Lingtong.

Afiliación

Wei X; Life Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.
Guo L; NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Cai H; Department of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Gu S; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Tang L; Department of Infectious Diseases Shulan (Hangzhou) Hospital Hangzhou China.
Leng Y; Department of Intensive Care Unit Peking University Third Hospital Beijing China.
Cheng M; Life Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.
He G; Department of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Han Y; Department of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Ren X; Department of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Lin B; Department of Critical Care Medicine, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Lv L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China.
Shao H; Department of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital; Zhengzhou University People's Hospital Henan University People's Hospital Zhengzhou China.
Wang M; Department of Critical Care Medicine, Henan Key Laboratory for Critical Care Medicine, Zhengzhou Key Laboratory for Critical Care Medicine, Henan Provincial People's Hospital; Zhengzhou University People's Hospital Henan University People's Hospital Zhengzhou China.
Wang H; Department of Emergency Intensive Care Unit The Fifth Clinical Medical College of Henan University of Chinese Medicine Zhengzhou China.
Dang D; Department of Critical Care Medicine Xi'an People's Hospital (Xi'an No.4 Hospital) Xi'an China.
Wang S; Department of Critical Care Medicine The Second Affiliated Hospital of Zhengzhou University Zhengzhou China.
Wang N; Department of Critical Care Medicine The Second Affiliated Hospital of Zhengzhou University Zhengzhou China.
Shen P; Department of Critical Care Medicine The First Hospital of Jiaxing Jiaxing China.
Wang Q; Department of Critical Care Medicine The First Hospital of Jiaxing Jiaxing China.
Xu Y; Department of Critical Care Medicine Taizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University Taizhou China.
Jiang Y; Department of Critical Care Medicine Taizhou Hospital of Zhejiang Province affiliated with Wenzhou Medical University Taizhou China.
Zhang N; Department of Critical Care Medicine Lishui People's Hospital Lishui China.
He X; Department of Critical Care Medicine Lishui People's Hospital Lishui China.
Deng X; Department of Critical Care Medicine Lishui People's Hospital Lishui China.
Dai M; Department of Critical Care Medicine Tongde Hospital of Zhejiang Province Hangzhou China.
Zhong L; Department of Critical Care Medicine The First People's Hospital of Pinghu Pinghu China.
Xiong Y; Department of Critical Care Medicine Lanxi Hospital of Traditional Chinese Medicine Lanxi China.
Pan Y; Department of Critical Care Medicine Wenzhou Central Hospital Wenzhou China.
Tang K; Department of Critical Care Medicine The First People's Hospital of Huzhou Huzhou China.
Liu F; Department of Critical Care Medicine The First People's Hospital of Huzhou Huzhou China.
Yang B; Center for Infectious Diseases Vision Medicals Co., Ltd. Guangzhou Guangdong China.
Ren L; NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Wang J; NHC Key Laboratory of Systems Biology of Pathogens and Christophe Mérieux Laboratory, National Institute of Pathogen Biology Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Jiang C; Life Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.
Huang L; Life Sciences Institute and Department of Critical Care Medicine of First Affiliated Hospital Zhejiang University Hangzhou China.

Imeta ; 3(4): e218, 2024 Aug.

Article en En | MEDLINE | ID: mdl-39135692

ABSTRACT

ABSTRACT

The MASS cohort comprises 2000 ICU patients with severe pneumonia, covering community-acquired pneumonia, hospital-acquired pneumonia, and ventilator-associated pneumonia, sourced from 19 hospitals across 10 cities in three provinces. A wide array of samples including bronchoalveolar lavage fluid, sputum, feces, and whole blood are longitudinally collected throughout patients' ICU stays. The cohort study seeks to uncover the dynamics of lung and gut microbiomes and their associations with severe pneumonia and host susceptibility, integrating deep metagenomics and transcriptomics with detailed clinical data.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Imeta Año: 2024 Tipo del documento: Article