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Long-wavelength triggered iridium(III) complex nanoparticles for photodynamic therapy against hypoxic cancer.
Liu, Shengnan; Wang, Ziwei; Wu, Zihan; Chen, Haoran; Zhu, Dongxia; Li, Gungzhe; Yan, Mingming; Bryce, Martin R; Chang, Yulei.
Afiliación
  • Liu S; Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, P. R. China. zhudx047@nenu.edu.cn.
  • Wang Z; Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, P. R. China. zhudx047@nenu.edu.cn.
  • Wu Z; Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, P. R. China. zhudx047@nenu.edu.cn.
  • Chen H; State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, Jilin Province 130033, China. yuleichang@ciomp.ac.cn.
  • Zhu D; Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, P. R. China. zhudx047@nenu.edu.cn.
  • Li G; Jilin Provincial Science and Technology Innovation Center of Health Food of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin Province 130117, P. R. China. 1993008106@qq.com.
  • Yan M; Jilin Provincial Science and Technology Innovation Center of Health Food of Chinese Medicine, Changchun University of Chinese Medicine, Changchun, Jilin Province 130117, P. R. China. 1993008106@qq.com.
  • Bryce MR; Department of Chemistry, Durham University, Durham, DH1 3LE, UK. m.r.bryce@durham.ac.uk.
  • Chang Y; State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun, Jilin Province 130033, China. yuleichang@ciomp.ac.cn.
Chem Commun (Camb) ; 60(73): 9938-9941, 2024 Sep 10.
Article en En | MEDLINE | ID: mdl-39171567
ABSTRACT
A long-wavelength triggered cationic iridium(III) complex, Ir5, and its corresponding nanoparticles with the ability to generate type I and type II reactive oxygen species have been synthesised. The complex targets mitochondria and achieves an excellent photodynamic therapy effect in hypoxic cancer cells.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Fármacos Fotosensibilizantes / Nanopartículas / Complejos de Coordinación / Iridio Límite: Humans Idioma: En Revista: Chem Commun (Camb) / Chem. commun. (Lond., 1996, Online) / Chemical communications (London. 1996. Online) Asunto de la revista: QUIMICA Año: 2024 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Fotoquimioterapia / Fármacos Fotosensibilizantes / Nanopartículas / Complejos de Coordinación / Iridio Límite: Humans Idioma: En Revista: Chem Commun (Camb) / Chem. commun. (Lond., 1996, Online) / Chemical communications (London. 1996. Online) Asunto de la revista: QUIMICA Año: 2024 Tipo del documento: Article