Indole triazene compound TU112 demonstrates in vitro activity against dormant Mycobacterium tuberculosis and efficacy against chronic tuberculosis infection in mice.

Shleeva, Margarita O; Nikonenko, Boris V; Majorov, Konstantin B; Ivanov, Pavel Yu; Apt, Alexander S; Velezheva, Valeria S

Shleeva, Margarita O; Nikonenko, Boris V; Majorov, Konstantin B; Ivanov, Pavel Yu; Apt, Alexander S; Velezheva, Valeria S.

Afiliación

Shleeva MO; A. N. Bach Institute of Biochemistry, Federal Research Centre "Fundamentals of Biotechnology", Moscow, Russia.
Nikonenko BV; Laboratory for Immunogenetics, Central Tuberculosis Research Institute, Moscow, Russia.
Majorov KB; Laboratory for Immunogenetics, Central Tuberculosis Research Institute, Moscow, Russia.
Ivanov PY; Institute for Element-Organic Chemistry Russian Academy of Sciences (INEOS RAS), Moscow, Russia.
Apt AS; Laboratory for Immunogenetics, Central Tuberculosis Research Institute, Moscow, Russia. Electronic address: alexapt0151@gmail.com.
Velezheva VS; Institute for Element-Organic Chemistry Russian Academy of Sciences (INEOS RAS), Moscow, Russia.

Tuberculosis (Edinb) ; 149: 102556, 2024 Aug 28.

Article en En | MEDLINE | ID: mdl-39226860

Palabras clave

Indole-based compound; Mouse TB model; Mycobacterial dormancy; Tuberculosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Tuberculosis (Edinb) Año: 2024 Tipo del documento: Article País de afiliación: Rusia

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