Facile construction of 2-pyrones under carbene catalysis.

Yu, Miao; Huang, Jie; Zhu, Haibin; Shi, Dongping; Yang, Weiqi; Liu, Yingjie; Ji, Yubin; Fu, Zhenqian

Yu, Miao; Huang, Jie; Zhu, Haibin; Shi, Dongping; Yang, Weiqi; Liu, Yingjie; Ji, Yubin; Fu, Zhenqian.

Afiliación

Yu M; Engineering Research Center for Medicine, Ministry of Education, Harbin University of Commerce Harbin 150076 China liuyj691@nenu.edu.cn jyb@hrbcu.edu.cn.
Huang J; Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering & Institute of Advanced Materials, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 China iamzqfu@njtech.edu.cn.
Zhu H; Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering & Institute of Advanced Materials, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 China iamzqfu@njtech.edu.cn.
Shi D; Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering & Institute of Advanced Materials, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 China iamzqfu@njtech.edu.cn.
Yang W; Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering & Institute of Advanced Materials, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 China iamzqfu@njtech.edu.cn.
Liu Y; Engineering Research Center for Medicine, Ministry of Education, Harbin University of Commerce Harbin 150076 China liuyj691@nenu.edu.cn jyb@hrbcu.edu.cn.
Ji Y; Engineering Research Center for Medicine, Ministry of Education, Harbin University of Commerce Harbin 150076 China liuyj691@nenu.edu.cn jyb@hrbcu.edu.cn.
Fu Z; Institute of Advanced Synthesis, School of Chemistry and Molecular Engineering & Institute of Advanced Materials, Nanjing Tech University 30 South Puzhu Road Nanjing 211816 China iamzqfu@njtech.edu.cn.

RSC Adv ; 14(39): 28585-28595, 2024 Sep 04.

Article en En | MEDLINE | ID: mdl-39247504

ABSTRACT

ABSTRACT

2-Pyrones are valuable structural motifs in organic chemistry, found in numerous natural products and pharmaceuticals. The synthesis of these heterocycles has been significantly advanced by the application of N-Heterocyclic Carbene (NHC) catalysis. This review examines the recent advancements in NHC-catalyzed synthesis of 2-pyrones, highlighting key methodologies, mechanisms, and synthetic applications. NHC catalysis has revolutionized the synthesis of 2-pyrones, providing efficient, selective, and versatile methods for constructing these valuable heterocycles.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: RSC Adv Año: 2024 Tipo del documento: Article