A blend of bacillus-fermented soybean meal, functional amino acids, and nucleotides improves nutrient digestibility, bolsters immune response, reduces diarrhea, and enhances growth performance in weaned piglets.
J Anim Sci
; 1022024 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-39320170
ABSTRACT
This study investigated the effects of a blend of bacillus-fermented soybean meal, functional amino acids, and nucleotides (Functional protein blend-FP Blend) as a replacement for animal protein sources in a weaner pig diet without antibiotic growth promoters on nutrient digestibility, blood profiles, intestinal morphology, diarrhea incidence, and growth performance. A total of 288 crossbred weaned piglets [â Duroc x â (Yorkshireâ
×â
Landrace)] with an average body weight (BW) of 6.89â
±â
0.71 kg were randomly allocated to 6 groups based on initial BW and sex (8 replicate pens per treatment; 3 gilts and 3 barrows/pen). The experiment lasted for 5 wk. Dietary treatments included PC [standard diet with 3% fish meal (FM) and 2% plasma protein (PP)], NC (nonanimal protein, AP), T1 (3% FM replaced with 5% FP Blend), T2 (3% FM and 1% PP replaced with 5% FP Blend), T3 (2% PP replaced with 5% FP Blend), and T4 (3% FM and 2% PP replaced with 5% FP Blend). Data were analyzed using Minitab version 17 software. Key results indicated that FP Blend improved the apparent ileal digestibility (AID) coefficient of dry matter, gross energy, lysine, and valine in T4 compared with NC treatment (Pâ
<â
0.05), whereas AID coefficient of crude protein and other amino acids remained constant (Pâ
>â
0.05). Compared with NC diet, the weaned pigs fed T4 diet reduced malondialdehyde, serum IL8, TNF-α, and increased IgG (Pâ
<â
0.05), while showing no effect on serum IL6, IL10, white blood cells, IgA, and endotoxin (Pâ
>â
0.05). Furthermore, FP blend significantly increased villus height in the duodenum and ileum in T4 compared with NC (Pâ
<â
0.05). The average daily gain (ADG) was highest in T4 (502.73 g/d), followed by T1 (477.96 g/d) and T2 (475.85 g/d), compared with PC (450.86 g/d) and NC (439.79 g/d). T4's ADG significantly differed from PC and NC (Pâ
<â
0.001), whereas no significant differences were observed in T1, T2, and T3 (Pâ
>â
0.05). The feed conversion ratio (FCR) was significantly lower in T4 (1.45) compared with PC (1.57) and NC (1.59) (Pâ
<â
0.001), with no significant differences among other groups. In conclusion, FP Blend demonstrated efficacy in improving nutrient digestibility, optimizing intestinal morphology, bolstering immune responses, reducing diarrhea incidence, alleviating the adverse effects of weaning stress, and enhancing growth performance of weaned piglets.
In this study, a blend of bacillus-fermented soybean meal, functional amino acids, and nucleotide (functional protein blend-FP Blend) was used as a substitute for animal protein sources in diets without antibiotic growth promoters. The novel findings revealed that the experimental piglets fed T4 diet exhibited the highest average daily gain (ADG) compared to those fed NC and PC diets. In addition, the FCR in T4 was significantly lower than that in NC and PC diets. FP Blend particularly improved the AID coefficient of dry matter, gross energy, lysine, methionine, and valine in T4. The positive impact of FP Blend extended to various blood parameters, including malondialdehyde, serum IL8, TNF-α, and IgG. Furthermore, FP Blend in T4 significantly increased villus height in both the duodenum and ileum when compared with the NC diet. In conclusion, the study demonstrates that FP Blend enhances growth performance, reduces FCR, improves nutrient digestibility, mitigates diarrhea incidence, optimizes intestinal morphology, bolsters immune responses, and alleviates the adverse effects of weaning stress in weaned piglets.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Glycine max
/
Diarrea
/
Dieta
/
Digestión
/
Aminoácidos
/
Alimentación Animal
/
Fenómenos Fisiológicos Nutricionales de los Animales
/
Nucleótidos
Límite:
Animals
Idioma:
En
Revista:
J Anim Sci
Año:
2024
Tipo del documento:
Article
País de afiliación:
Vietnam