Prognostic value of atypical B cells in breast cancer.

García-Torralba, Esmeralda; Galluzzi, Lorenzo; Buqué, Aitziber

García-Torralba, Esmeralda; Galluzzi, Lorenzo; Buqué, Aitziber.

Afiliación

García-Torralba E; Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USA; Department of Medical Oncology, Hospital Universitario Morales Meseguer, Murcia, Spain; Department of Medicine, Medical School, University of Murcia, Murcia, Spain; IMIB-Arrixaca, Murcia, Spain.
Galluzzi L; Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USA. Electronic address: deadoc80@gmail.com.
Buqué A; Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USA. Electronic address: abuquemartinez@gmail.com.

Trends Cancer ; 2024 Sep 30.

Article en En | MEDLINE | ID: mdl-39353814

ABSTRACT

ABSTRACT

The impact of tumor-infiltrating B cells on breast cancer (BRCA) outcomes remains poorly understood. Recent findings from Yang et al. identify an atypical, clonally expanded population of activated Fc receptor-like 4 (FCRL4)+ B cells that is associated with improved overall survival in patients affected by various tumor types, including BRCA.

Palabras clave

ABCs; CD8(+) cytotoxic T lymphocytes; TNBC; antigen presentation; germinal center; tertiary lymphoid structures

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Trends Cancer Año: 2024 Tipo del documento: Article País de afiliación: España

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