Inability of Ni++ and Co++ to release histamine from rat peritoneal mast cells.
Res Commun Chem Pathol Pharmacol
; 10(2): 383-6, 1975 Feb.
Article
en En
| MEDLINE
| ID: mdl-50613
ABSTRACT
Ni++ and Co++ concentrations from 10 minus 3M to 10 minus 6M were added to rat peritoneal mast cells. These metal ions, at the concentrations indicated, did not cause histamine release from the mast cells, and did not inhibit the histamine release mediated by compound 48/80. On the basis of these studies, anaphylactoid edema of the rat following injection of i++ or Co++ is on a basis other than a direct effect of the m-tal ion on mast cells.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cobalto
/
Gránulos Citoplasmáticos
/
Liberación de Histamina
/
Mastocitos
/
Níquel
Límite:
Animals
Idioma:
En
Revista:
Res Commun Chem Pathol Pharmacol
Año:
1975
Tipo del documento:
Article