Studies of antigens in Plasmodium yoelii. II. Inheritance and recombination of antigenic characters.
Parasitology
; 89 ( Pt 1): 27-34, 1984 Aug.
Article
en En
| MEDLINE
| ID: mdl-6206454
ABSTRACT
The inheritance of an antigen designated Py-1 in the rodent malaria parasite Plasmodium yoelii has been investigated. A cross was made between 2 lines differing in the electrophoretic mobility and quantity of Py-1 detected by crossed immunoelectrophoresis. In 10 clones isolated from the progeny of the cross the level of Py-1 always correlated with the virulence of the infection and it was concluded that these characters were different phenotypic effects of the same gene mutation. The electrophoretic mobility of Py-1 segregated independently of the virulence character and was therefore controlled by a different gene. These two antigenic markers also recombined with isoenzyme and drug-sensitivity characters distinguishing the parent lines.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
3_ND
Problema de salud:
3_malaria
Asunto principal:
Plasmodium
/
Genes
/
Epítopos
Límite:
Animals
Idioma:
En
Revista:
Parasitology
Año:
1984
Tipo del documento:
Article