The modified nucleotide constituents of human prostatic cancer cell (MA-160) poly(A)-containing RNA.
Biochim Biophys Acta
; 608(1): 1-18, 1980 Jun 27.
Article
en En
| MEDLINE
| ID: mdl-6248114
ABSTRACT
Cytoplasmic poly A(+) RNA from human prostatic cancer cells grown in the presence of 32P was isolated by affinity chromatography on columns of oligo(dT)-cellulose. The RNA was digested with RNAase T2 and the products of digestion were fractionated by two-dimensional electrophoresis. The resulting autoradiograms revealed the presence of many different cap groups as well as two internal modified nucleotide components. 19 different type 1 and type 2 'cap' groups were identified. The internal modified nucleotides were N6-methyl adenosine and a 2'-O-methyl nucleotide possessing an unusual modified base.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Poli A
/
Neoplasias de la Próstata
/
Ribonucleótidos
/
ARN Mensajero
/
ARN Neoplásico
/
Endorribonucleasas
Límite:
Humans
/
Male
Idioma:
En
Revista:
Biochim Biophys Acta
Año:
1980
Tipo del documento:
Article