Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization.
J Antibiot (Tokyo)
; 36(6): 639-45, 1983 Jun.
Article
en En
| MEDLINE
| ID: mdl-6874585
ABSTRACT
A strain of Streptomyces was found to produce new antifungal antibiotics. The active compounds were purified and separated into two substances named leptomycin A and B by high performance liquid chromatography. The molecular formulae of leptomycins A and B are C32H46O6 and C33H48O6 respectively, and physicochemical and biological properties of them are very similar to each other. Leptomycins A and B exhibit strong inhibitory activity against Schizosaccharomyces and Mucor.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Bacterias
/
Antifúngicos
Idioma:
En
Revista:
J Antibiot (Tokyo)
Año:
1983
Tipo del documento:
Article