Mammals have multiple genes for individual ribosomal proteins.
Cell
; 24(2): 301-6, 1981 May.
Article
en En
| MEDLINE
| ID: mdl-7237549
ABSTRACT
The reiteration frequency of the genes that encode the structural proteins of the mammalian ribosome was studied with a set of cloned cDNA probes containing several different mouse r-protein mRNA sequences. Results from a reassociation kinetics analysis, Southern blotting experiments and gene cloning studies collectively indicate that each individual r-protein species is represented by multiple genes in mammals. Among the examples studied, the multiplicity of mouse r-protein genes varied from about 7 to 20, a striking contrast to the low copy numbers observed in less evolutionarily advanced eucaryotes. The multiplicity of individual r-protein genes in humans and rodents is similar.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Proteínas Ribosómicas
/
Genes
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Cell
Año:
1981
Tipo del documento:
Article