[Transurethral microwave-thermotherapy in the treatment of benign prostatic hyperplasia]. / Transurethrale microgolf-thermotherapie bij de behandeling van benigne prostaathyperplasie.
Ned Tijdschr Geneeskd
; 138(35): 1764-70, 1994 Aug 27.
Article
en Nl
| MEDLINE
| ID: mdl-7523961
ABSTRACT
OBJECTIVE:
Determining the therapeutic efficacy of transurethral microwave thermotherapy (TUMT) in benign prostatic hyperplasia (BPH).DESIGN:
Prospective.SETTING:
Department of Urology, University Hospital Nijmegen, the Netherlands.METHOD:
In the outpatient clinic, 130 BPH patients (mean age 65.9 years (SD 6.9); mean prostatic volume 50.2 cm3 (SD 18.4)) received TUMT in a single session lasting 60 min. The prostate was heated to above 45 degrees C by a microwave antenna in a urethral catheter, resulting in tissue necrosis. In the first year after treatment the Madsen symptom score, maximal flow, residual volume, prostatic volume and concentration of prostate-specific antigen in blood were collected.RESULTS:
After 1 year 98 patients could be evaluated; of the other 32, 16 withdrew from follow-up, 10 underwent transurethral prostate resection and 6, other treatment. The maximal flow increased by 1.2 ml/s (SD 4.0). The residual volume decreased by 15.8 ml (SD 55.6). Symptom scores improved by 5.9 points (SD 5.0). A 50% increase in symptom score was seen in 49.5% of all patients; 24.3% showed no improvement of complaints. There was no change in prostatic volume, whereas PSA concentration showed a transient increase in the first week after TUMT. Preliminary results after 6 months' follow-up of a randomised placebo-controlled study in 50 patients showed subjective and objective improvement of miction.CONCLUSION:
TUMT results in distinct subjective improvement. Urodynamic findings show a less pronounced improvement.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Hiperplasia Prostática
/
Hipertermia Inducida
/
Microondas
Tipo de estudio:
Clinical_trials
/
Observational_studies
Límite:
Aged
/
Aged80
/
Humans
/
Male
/
Middle aged
Idioma:
Nl
Revista:
Ned Tijdschr Geneeskd
Año:
1994
Tipo del documento:
Article