[Electron microscopic study on the petechial hemorrhagic spots in patients with epidemic hemorrhage fever (EHF)].
Zhonghua Bing Li Xue Za Zhi
; 23(6): 361-3, 1994 Dec.
Article
en Zh
| MEDLINE
| ID: mdl-7720117
ABSTRACT
EHF viral particles were found in the squamous epithelial cells and capillary endothelial cells of the petechial spots located at the mucous membrane of the soft palate in cases of early stage of severe type EHF by transmission electron microscopy. The viral particles are round or oval in shape, about 100 nm in diameter with a lipid bilayer envelope from which spikes are protruding. The virions matured by budding through the intracytoplasmic membranes into the smooth surfaced vesicles. The morphological characteristics of the virion coincided with the viral particles of Family Bunyaviridae. It was the first time to demonstrate that the squamous epithelial cells of the soft palate is one of the target cells in EHF virus infection and to describe the subcellular morphological evidence of the petechial spots at the soft palate by EM.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Virus Hantaan
/
Fiebre Hemorrágica con Síndrome Renal
/
Mucosa Bucal
Límite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhonghua Bing Li Xue Za Zhi
Año:
1994
Tipo del documento:
Article