Hepatic regeneration: current concepts and clinical implications.
Semin Liver Dis
; 14(2): 190-210, 1994 May.
Article
en En
| MEDLINE
| ID: mdl-8047902
ABSTRACT
Liver regeneration occurs as a result of hepatic tissue loss or injury. The process of liver regeneration is carefully regulated in a controlled biologic scheme with closely interactive relationships between hormones, free neurotransmitters, and nutrients; protooncogenes; and polypeptide and glycolipid growth factors. These relationships are now being studied at the molecular and cellular levels and attempts are being made to reconstruct the complete intricate process. Although significant breakthroughs have occurred in understanding the effects and regulation of several subsystems (such as insulin and its receptors; TGF-alpha and TGF-beta; HGF and its receptors), the integral process remains a mystery. Improved comprehension of the regeneration process will lead to rational treatment algorithms for now dreaded hepatic diseases.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Regeneración Hepática
Límite:
Humans
Idioma:
En
Revista:
Semin Liver Dis
Año:
1994
Tipo del documento:
Article