Presence of serum antibodies to coagulation protein C in patients with systemic lupus erythematosus is not associated with antigenic or functional protein C deficiencies.

Ruiz-Arguelles, A; Vazquez-Prado, J; Deleze, M; Perez-Romano, B; Drenkard, C; Alarcon-Segovia, D; Ruiz-Arguelles, G J

Ruiz-Arguelles, A; Vazquez-Prado, J; Deleze, M; Perez-Romano, B; Drenkard, C; Alarcon-Segovia, D; Ruiz-Arguelles, G J.

Afiliación

Ruiz-Arguelles A; Laboratorios Clinicos de Puebla, Instituto Nacional de la Nutricion Salvador Zubiran, Mexico City, Mexico.

Am J Hematol ; 44(1): 58-9, 1993 Sep.

Article en En | MEDLINE | ID: mdl-8342565

ABSTRACT

ABSTRACT

Antibodies directed to immunopurified coagulation protein C (PC) were investigated in serum samples from 108 patients with systemic lupus erythematosus (SLE) and found in 12 of them. However, their presence was not associated with antigenic or functional deficiencies of PC, which were documented in 6 and 17 patients, respectively.

Asunto(s)

Anticuerpos/análisis; Coagulación Sanguínea/fisiología; Lupus Eritematoso Sistémico/inmunología; Deficiencia de Proteína C; Proteína C/inmunología; Anticuerpos/inmunología; Ensayo de Inmunoadsorción Enzimática; Femenino; Humanos; Lupus Eritematoso Sistémico/sangre; Proteína C/fisiología

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Coagulación Sanguínea / Proteína C / Deficiencia de Proteína C / Lupus Eritematoso Sistémico / Anticuerpos Tipo de estudio: Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Am J Hematol Año: 1993 Tipo del documento: Article País de afiliación: México

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