Association between HLA antigens and families with psoriasis vulgaris.
Chin Med J (Engl)
; 106(2): 132-5, 1993 Feb.
Article
en En
| MEDLINE
| ID: mdl-8504697
ABSTRACT
This paper typed HLA-A, B, C and DR antigens in patients with psoriasis vulgaris and healthy persons in 12 families. The phenotype frequencies of HLA-A1, B13, B17, Cw4 and Cw6 in the patients were higher than those in the controls. The analysis of haplotype segregation showed that HLA haplotypes in families with more psoriatic cases were marked deviation from random distribution. One or two HLA haplotypes sharing among affected siblings occurred more frequently than expected. The result of Lods score for six families showed that there was a close linkage between the gene of psoriasis vulgaris and HLA antigens. The gene of psoriasis was coincided with the recessive hereditary mode.
Buscar en Google
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Psoriasis
/
Antígenos HLA-C
/
Antígenos HLA
Tipo de estudio:
Risk_factors_studies
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Chin Med J (Engl)
Año:
1993
Tipo del documento:
Article