[Estimation of effectiveness of antiemetic treatment with Zofran given in one dose to children with neoplasms]. / Ocena skutecznosci leczenia przeciwwymiotnego Zofranem podawanym w jednorazowej dawce dziennej dzieciom z choroba nowotworowa.
Pediatr Pol
; 70(11): 925-8, 1995 Nov.
Article
en Pl
| MEDLINE
| ID: mdl-8677158
Clinical studies of antiemetic treatment with Zofran in children suffering from neoplastic diseases are presented. The studies were carried out in 33 children aged 3 months to 17 years treated in 1993. The majority of the patients were treated for ALL (20), Hodgkins disease (3), nephroblastoma (3), non-Hodgkin lymphoma (2), solid tumors (5). Two-hundred thirty-eight cycles of chemotherapy with cystostatics having varied emetic effects were carried out in these children. Zofran was given in one dose, one hour before chemotherapy in a dose of 4 or 8 mg. The intensity of vomiting was assessed according to the WHO 5-grade scale. O to 1 grade of vomiting was observed in 84.4%, 2nd grade in 15.2%. There were no cases of 3rd or 4th grade vomiting. No side-effects of the medication were observed in the studied group. It was found that Zofran is an effective and well-tolerated antiemetic medication in children on chemotherapy.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vómitos
/
Ondansetrón
/
Antieméticos
/
Neoplasias
Tipo de estudio:
Etiology_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
Pl
Revista:
Pediatr Pol
Año:
1995
Tipo del documento:
Article