The effects of methaqualone on the temperature regulation of mice.
Res Commun Chem Pathol Pharmacol
; 17(1): 41-52, 1977 May.
Article
en En
| MEDLINE
| ID: mdl-877405
ABSTRACT
Methaqualone produces dose and time dependent changes in the rectal temperature of mice. More specifically, the drug produces poikilothermia. This effect appears to be produced by methaqualone itself rather than a liver metabolite since SKF525A, a compound known to block drug metabolizing enzymes in the liver, does not abolish the phenomenon. Tolerance to the temperature altering effects of methaqualone is also shown.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Regulación de la Temperatura Corporal
/
Metacualona
Límite:
Animals
Idioma:
En
Revista:
Res Commun Chem Pathol Pharmacol
Año:
1977
Tipo del documento:
Article