Optimizing sodium balance in hemodialysis.
Blood Purif
; 14(2): 115-27, 1996.
Article
en En
| MEDLINE
| ID: mdl-8785027
ABSTRACT
this paper develops and tests a mathematical model for Na+ kinetics applied to standard hemodialysis. The volume of distribution of exchangeable Na+, dialyzer surface area, blood and dialysis fluid flow rate, target weight loss, treatment duration and the Na+ diffusibility constant are taken into account. The model is used to compute the optimal hour by hour dialysis fluid Na+ concentration required to achieve the prescribed end-dialysis natremia and maintain a constant end-dialysis body Na+ pool, while providing a nearly uniform removal of Na+ over dialysis. The model was preliminary tested on 10 consecutive dialyses in a single patient using special dialyzer which generates a part of ultrafiltrate uncontaminated by dialysate.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Sodio
/
Diálisis Renal
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Blood Purif
Año:
1996
Tipo del documento:
Article
País de afiliación:
Italia