B cell-deficient muMT mice as an experimental model for Mycoplasma infections in X-linked agammaglobulinemia.
Eur J Immunol
; 27(8): 2118-21, 1997 Aug.
Article
en En
| MEDLINE
| ID: mdl-9295053
ABSTRACT
B cell-deficient muMT mice were investigated as an experimental model for human X-linked agammaglobulinemia (XLA). Mice were intranasally infected with Mycoplasma pulmonis and in 16 out of 17 muMT mice, dissemination of the bacteria from the airways was observed. More than 50% of these mice developed arthritis and/or changes in periarticular tissues. Mycoplasmal infection in muMT mice thus resembles the disease seen in XLA patients implying the usefulness of the model.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cromosoma X
/
Agammaglobulinemia
/
Ligamiento Genético
/
Infecciones por Mycoplasma
Tipo de estudio:
Etiology_studies
Límite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Eur J Immunol
Año:
1997
Tipo del documento:
Article
País de afiliación:
Suecia