Red cell aplasia caused by parvovirus B19 in AIDS: use of i.v. immunoglobulin.
Ann Hematol
; 75(1-2): 67-8, 1997.
Article
en En
| MEDLINE
| ID: mdl-9322687
ABSTRACT
We describe the case of a 34-year-old man with AIDS who developed severe anemia due to chronic pure red cell aplasia (PRCA) caused by parvovirus B19. Following initial treatment with an infusion of intravenous immunoglobulin (IVIg), 1 g/kg, PRCA resolved, but there was a recurrence of severe anemia in 3 months. Retreatment with 2 g/kg IVIg over 2 days resulted in normalization of hemoglobin and a significantly longer remission duration. Two doses of 0.4 g/kg IVIg q 4 wk failed to prevent a relapse of PRCA in our patient. The dose and schedule of IVIg in the treatment of PRCA caused by parvovirus B19 in AIDS requires further definition.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Parvovirus B19 Humano
/
Inmunoglobulinas Intravenosas
/
Aplasia Pura de Células Rojas
/
Infecciones Oportunistas Relacionadas con el SIDA
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Ann Hematol
Asunto de la revista:
HEMATOLOGIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Estados Unidos