Treating antidepressant nonresponders with augmentation strategies: an overview.
J Clin Psychiatry
; 59 Suppl 5: 5-12; discussion 13-5, 1998.
Article
en En
| MEDLINE
| ID: mdl-9635543
This paper provides an overview of antidepressant nonresponse and the role of augmentation strategies in the management of treatment-resistant depression. When effective, the more widely used augmentation strategies, including lithium salts, thyroid hormones, pindolol, buspirone, and psychostimulants, share two important advantages when compared with "switching" strategies: avoidance of ill effects associated with discontinuing the initial antidepressant and rapidity of onset of action. Ideally, advances in the understanding of the neurobiology of mood disorders and mechanisms of antidepressant response will permit a more efficient and specific matching between patient, initial antidepressant, and subsequent strategy for enhancing response to treatment.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Trastorno Depresivo
/
Antidepresivos
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
J Clin Psychiatry
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos