The beginning of the end of the antibiotic era? Part I. The problem: abuse of the "miracle drugs".
Quintessence Int
; 29(3): 151-62, 1998 Mar.
Article
en En
| MEDLINE
| ID: mdl-9643250
ABSTRACT
The antibiotic era began in the early 1940s with the clinical use of penicillin. Subsequent discovery, development, and clinical use of other antibiotics resulted in effective therapy against major bacterial pathogens. These drugs were so effective that bacterial infectious diseases were considered by many experts to be under complete therapeutic control. However, the scientific community grossly underestimated the remarkable genetic plasticity of these organisms and their ability, through mutations and genetic transfer, to develop resistance to antibiotics. Infectious diseases are now the world's major cause of death. The cause of bacterial reemergence as a threat to human health and life is the abuse of the "miracle drugs." The ubiquitous nature of antibiotics in the human ecosystem foments bacterial resistance and threatens to eliminate antibiotics as effective drugs for human therapeutic use.
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Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
4_TD
Problema de salud:
2_enfermedades_transmissibles
/
4_antimicrobial_resistance
Asunto principal:
Farmacorresistencia Microbiana
/
Utilización de Medicamentos
/
Antibacterianos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Quintessence Int
Año:
1998
Tipo del documento:
Article
País de afiliación:
Estados Unidos