[Pontine and extra-pontine myelinolysis. Early diagnostic and prognostic value of cerebral CT and MRI]. / Pontine und extrapontine Myelinolysen. Frühdiagnostischer und prognostischer Wert von zerebralem CT und MRT.
Nervenarzt
; 69(12): 1083-90, 1998 Dec.
Article
en De
| MEDLINE
| ID: mdl-9888145
ABSTRACT
Retrospective examination of 44 patients with central pontine and/or extrapontine myelinolysis leads to the conclusion that in early diagnostics cerebral NMR is superior to cCT. T2-weighted images turned out to be the most sensitive parameter. Frequent contrast-medium enhancement early in the course up to 4 weeks after clinical manifestation in 7 patients underlines the pathogenetic idea of an initial transient blood-brain barrier. According to our results, central-pontine myelinolysis (CPM) proof by NMR can be expected after 1 week. During the clinical course, cCT and NMR findings showed no regression. Also no connection was noted between the size of the pontine lesion and the favorable clinical course in 72.2% of the patients, nor was there a correlation with the extent of the neurological symptoms at the crisis of the disease. Altogether, cCT and NMR are irrelevant for the prognosis of cerebral myelinolysis.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Imagen por Resonancia Magnética
/
Tomografía Computarizada por Rayos X
/
Mielinólisis Pontino Central
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adult
/
Aged
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Aged80
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Female
/
Humans
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Male
/
Middle aged
Idioma:
De
Revista:
Nervenarzt
Año:
1998
Tipo del documento:
Article