Neuronal correlates of vestibulo-ocular reflex adaptation in the alert guinea-pig.
Eur J Neurosci
; 11(5): 1827-30, 1999 May.
Article
em En
| MEDLINE
| ID: mdl-10215935
ABSTRACT
The spiking behaviour of 66 second-order vestibular neurons was studied in alert, chronically prepared guinea-pigs during the horizontal vestibulo-ocular reflex (VOR). Among the 66 studied neurons, seven were held long enough (> 1 h) to compare their spiking behaviour before and after a training procedure inducing a decrease in the gain of the VOR. When tested in darkness following adaptation, five of them showed a significant decrease of their sensitivity to head rotation. However, the resting discharge of these five neurons remained unchanged. This suggests that VOR adaptation is mediated not only by changes in synaptic efficacities but also by modifications in the spike generator which transforms synaptic inputs into a pattern of action potentials.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Reflexo Vestíbulo-Ocular
/
Adaptação Fisiológica
/
Neurônios Aferentes
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Eur J Neurosci
Assunto da revista:
NEUROLOGIA
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
França